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Carisoprodol carisoprodol tablet [package insert]. Philadelphia, Pa. Accessed January 14, Chlorzoxazone chlorzoxazone tablet [package insert]. Sellersville, Pa. Cyclobenzaprine hydrochloride cyclobenzaprine hydrochloride tablet [package insert].
Corona, Calif. Diazepam diazepam tablet [package insert]. Miami, Fla. Skelaxin metaxalone [package insert]. Briston, Tenn. Methocarbamol methocarbamol tablet [package insert]. January 14, Orphenadrine citrate extended-release orphenadrine citrate tablet [package insert]. Princeton, NJ: Sandoz, Inc.
Tizanidine hydrochloride tizanidine hydrochloride tablet [package insert]. Pomona, NY: Barr Laboratories. United States Food and Drug Administration. Zanaflex tizanidine hydrochloride tablets and capsules. Top brand-name drugs by units in Top generic drugs by units in Diagnosis and treatment of low back pain: a joint clinical practice guideline from the American College of Physicians and the American Pain Society [published correction appears in Ann Intern Med.
Ann Intern Med. National Headache Foundation. National Headache Foundation standards of care for headache diagnosis and treatment. Chicago, Ill. Treatment of fibromyalgia with cyclobenzaprine: a meta-analysis.
Arthritis Rheum. EULAR evidence-based recommendations for the management of fibromyalgia syndrome. Ann Rheum Dis. Prescription of nonsteroidal anti-inflammatory drugs and muscle relaxants for back pain in the United States. Muscle relaxants for non-specific low back pain.
Cochrane Database Syst Rev. Comparative efficacy and safety of skeletal muscle relaxants for spasticity and musculoskeletal conditions: a systematic review. J Pain Symptom Manage. Diamond S. Double-blind study of metaxalone; use as a skeletal-muscle relaxant. Chou R, Huffman LH. Activity of tetrazepam in low back pain. Clin Trials J. Treatment of chronic low-back syndrome with tetrazepam in a placebo controlled double-blind trial.
J Drug Dev. Scheiner JJ. Cyclobenzaprine in the treatment of local muscle spasm. Minneapolis, Minn. Aiken DW. A comparative study of the effects of cyclobenzaprine, diazepam, and placebo on acute skeletal muscle spasm of local origin.
Brown BR jr, Womble J. Cyclobenzaprine in intractable pain syndrome with muscle spasms. Basmajian JV. Cyclobenzaprine hydrochloride effect on skeletal muscle spasm in the lumbar region and neck: two double-blind controlled clinical laboratory studies. Arch Phys Med Rehabil. What is it used for? Can it be used to treat opiate withdrawal? Does it cause any side effects? Does it interact with other medications? Are there any other risks or warnings? Is it addictive? Is overdose possible?
The bottom line. Read this next. Medically reviewed by Zara Risoldi Cochrane, Pharm. The 7 Best Natural Muscle Relaxers. Medically reviewed by Debra Rose Wilson, Ph. Treating Pain with Heat and Cold. Flexeril is a brand name for cyclobenzaprine, a commonly prescribed muscle relaxant for muscle pain and other musculoskeletal conditions.
Cyclobenzaprine is available in immediate-release and extended-release forms. Robaxin and Flexeril are both muscle relaxants. However, they are not the same drug. Robaxin contains methocarbamol and is usually dosed multiple times per day. Flexeril contains cyclobenzaprine and is available in an extended-release form that can be taken once per day. Robaxin and Flexeril are comparable in effectiveness. Some people may prefer extended-release generic Flexeril for its once-daily dosing.
But, Flexeril may also cause more adverse effects like drowsiness and dry mouth. Discuss these treatment options with a doctor to find the best medication for you. There are no adequate studies to show that Robaxin or Flexeril are safe or harmful during pregnancy. These medications should only be taken if their benefits outweigh the risks.
Muscle relaxants should only be taken with medical guidance from a doctor. It is not recommended to consume alcohol while on Robaxin or Flexeril. Alcohol can compound muscle-relaxant side effects such as drowsiness, dizziness, or loss of coordination.
According to systematic reviews, almost all muscle relaxers are comparable in effectiveness. Cyclobenzaprine and tizanidine may be more sedating.
However, cyclobenzaprine is one of the most studied muscle relaxers with strong evidence for its effectiveness. Skip to main content Search for a topic or drug. Robaxin vs. Flexeril: Differences, similarities, and which is better for you.
By Gerardo Sison, Pharm. Want the best price on Robaxin? Top Reads in Drug vs. Toujeo vs Lantus: Main Differences and S Dulera vs Advair: Main Differences and S Suboxone vs Methadone: Main Differences
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